Palbociclib formulation containing glucono delta lactone

The present invention relates to a pharmaceutical solid composition, containing palbociclib or a pharmaceutically acceptable salt thereof; gluconic acid and/or derivative thereof; and optionally one or more further water-soluble acids. The composition shows improved dissolution properties, compared...

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Bibliographic Details
Main Authors MEHTA, GAURAV BHUPENDRABHAI, CHAWLA, MANISH, GATTANI, YOGESH SEVARAMJI, GUPTA, VIJENDER
Format Patent
LanguageChinese
English
Published 01.03.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a pharmaceutical solid composition, containing palbociclib or a pharmaceutically acceptable salt thereof; gluconic acid and/or derivative thereof; and optionally one or more further water-soluble acids. The composition shows improved dissolution properties, compared to prior art compositions.
Bibliography:Application Number: TW202312124812