Nitrogen-containing fused three ring PRMT5 inhibitor, and preparation method therefor and pharmaceutical use thereof

A PRMT5 inhibitor having a structure of formula (I), a preparation method therefor, a pharmaceutical composition containing same, the use thereof as a PRMT5 inhibitor, and the use thereof in the treatment and/or prevention of PRMT5-mediated diseases.

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Bibliographic Details
Main Authors XU, YAOCHANG, LIU, ZHAO-MIN, YANG, FEI, YU, HONGPING, DENG, HAI-BING, CHEN, ZHUI
Format Patent
LanguageChinese
English
Published 16.02.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A PRMT5 inhibitor having a structure of formula (I), a preparation method therefor, a pharmaceutical composition containing same, the use thereof as a PRMT5 inhibitor, and the use thereof in the treatment and/or prevention of PRMT5-mediated diseases.
Bibliography:Application Number: TW202312128632