Transcriptional regulators of the TEAD family

The present disclosure relates to transcriptional signatures obtained on a set of genes comprising any of 220 to 249 of a set of genes (1) and any of 210 to 233 of a set of genes (2) from a TEAD-500 signature and its use for determining the TEAD-activity of a cancer. The transcriptional signatures a...

Full description

Saved in:
Bibliographic Details
Main Author SPANAKIS, EMMANUEL
Format Patent
LanguageChinese
English
Published 16.01.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The present disclosure relates to transcriptional signatures obtained on a set of genes comprising any of 220 to 249 of a set of genes (1) and any of 210 to 233 of a set of genes (2) from a TEAD-500 signature and its use for determining the TEAD-activity of a cancer. The transcriptional signatures are useful in a variety of applications, including, predicting the likelihood that a subject will respond to a TEAD-pathway inhibitor treatment, selecting patients for clinical trials, assessing efficacy of TEAD-pathway inhibitor molecules, and prognosing survival, response to, and benefit from anti-TEAD pathway treatments.
Bibliography:Application Number: TW202312110695