Di-cyclopropyl based IL-17A modulators and uses thereof

The disclosure herein provides compounds and pharmaceutical compositions of Formula (I) and Formula (I-A) for the modulation of IL-17A. Compounds and pharmaceutical compositions of Formula (I) and Formula (I-A) are useful for the treatment of inflammatory conditions, such as psoriasis.

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Bibliographic Details
Main Authors FATHEREE, PAUL R, PAULICK, MARGOT G, CHURCH, TIMOTHY J, REILLY, MAUREEN, LINSELL, MARTIN S
Format Patent
LanguageChinese
English
Published 01.12.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure herein provides compounds and pharmaceutical compositions of Formula (I) and Formula (I-A) for the modulation of IL-17A. Compounds and pharmaceutical compositions of Formula (I) and Formula (I-A) are useful for the treatment of inflammatory conditions, such as psoriasis.
Bibliography:Application Number: TW20230106593