Cas12a nickases

The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof...

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Bibliographic Details
Main Authors VAN DER OOST, JOHN, WU, WEN YING, WARREN, RICARDO VILLEGAS, STAALS, RAYMOND HUBERT JOSEPHE, MEULEWAETER, FRANK, D'HALLUIN, KATELIJN, LUTEIJN, MAARTJE JANNEKE, DE VLEESSCHAUWER, DAVID
Format Patent
LanguageChinese
English
Published 01.11.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof.
Bibliography:Application Number: TW20230107412