RXFP1 agonists

The disclosure relates to compounds of Formula (I), which are RXFP1 receptor agonists, compositions containing them, and methods of using them, for example, in the treatment of heart failure, fibrotic diseases, and related diseases such as lung disease (e.g., idiopathic pulmonary fibrosis), kidney d...

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Main Authors LAWRENCE, R. MICHAEL, ORWAT, MICHAEL J, POTTURI, HIMA KIRAN, PABBISETTY, KUMAR BALASHANMUGA, SHAW, SCOTT A, PINTO, DONALD J.P, FRIENDS, TODD J, HEGDE, SUBRAMANYA, VOKITS, BENJAMIN P, KUMAR, SREEKANTHA RATNA, TORA, GEORGE O, FINLAY, HEATHER, MYERS, MICHAEL C, LI, JIANQING, BILDER, DONNA M, MATHUR, ARVIND, O'MALLEY, DANIEL, WURTZ, NICHOLAS R, BHOGADI, VIKRAM, PASUNOORI, LAXMAN, SMITH II, LEON M, CLARKE, ADAM JAMES, SRINIVAS, PITANI VEERA VENKATA, SU, SHUN
Format Patent
LanguageChinese
English
Published 01.09.2023
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Summary:The disclosure relates to compounds of Formula (I), which are RXFP1 receptor agonists, compositions containing them, and methods of using them, for example, in the treatment of heart failure, fibrotic diseases, and related diseases such as lung disease (e.g., idiopathic pulmonary fibrosis), kidney disease (e.g., chronic kidney disease), or hepatic disease (e.g., non-alcoholic steatohepatitis and portal hypertension).
Bibliography:Application Number: TW20220141101