Combination therapy for treating lung cancer

The present invention relates to methods for treating small cell lung cancer (SCLC), in particular small cell lung cancer (SCLC) in a subject in need thereof wherein a therapeutically efficient amount of a radiopharmaceutical compound comprising a SSTR binding moiety, in particular [177Lu]Lu-DOTATE...

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Bibliographic Details
Main Authors AIMONE, PAOLA DANIELA, CHICCO, DANIELA, FOLITAR, ILYA, MARIANI, MAURIZIO F
Format Patent
LanguageChinese
English
Published 16.05.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to methods for treating small cell lung cancer (SCLC), in particular small cell lung cancer (SCLC) in a subject in need thereof wherein a therapeutically efficient amount of a radiopharmaceutical compound comprising a SSTR binding moiety, in particular [177Lu]Lu-DOTATE is administered to said subject in combination with one or more chemotherapeutic agents, such as carboplatin and etoposide, and, optionally an immune-oncology (I/O) agent, such as tislelizumab.
Bibliography:Application Number: TW202211143045