Intratumoral alpha-emitter radiation in combination with immune checkpoint regulators

A substance which regulates immune-checkpoints for use as a medicament for treatment of a tumor of a patient wherein the administration pattern of the medicament comprises administering a therapeutically effective amount of the substance to the tumor, in one or more sessions, and implanting seeds (2...

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Main Authors DEN, ROBERT, SHAI, AMIT, ROUMANI, SARA DEL MARE, MANSOUR, FAIRUZ, KEISARI, YONA, NISHRI, YOSSI, SEGAL, RONEN, EFRATI, MARGALIT, DOMANKEVICH, VERED, KELSON, ITZHAK
Format Patent
LanguageChinese
English
Published 01.05.2023
Subjects
ELECTROTHERAPY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
RADIATION THERAPY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
ULTRASOUND THERAPY
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Summary:A substance which regulates immune-checkpoints for use as a medicament for treatment of a tumor of a patient wherein the administration pattern of the medicament comprises administering a therapeutically effective amount of the substance to the tumor, in one or more sessions, and implanting seeds (204) carrying radium-224 in the tumor for intratumoral alpha-emitter radiotherapy less than two weeks from administering the substance.
Bibliography:Application Number: TW202211122840