ROR1 and B7-H3 binding antibody-drug conjugate and use thereof

The present invention relates to antibody-drug conjugate(ADC) that binds to ROR1 and B7-H3, uses for such ADCs, specifically the present invention relates to an antibody-drug conjugate comprising a bispecific antibody that specifically binds to ROR1 and B7-H3; and uses for such ADCs in treatment and...

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Main Authors KIM, JU-HEE, YOO, BYEON-MIN, LEE, BO-RA, KWON, JUNG-A, LEE, SU-YOUN, JUNG, JIN-WON, RYU, HYUN-MIN, SONG, HO-YOUNG, PARK, YUN-HEE, CHUNG, CHUL-WOONG
Format Patent
LanguageChinese
English
Published 01.04.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to antibody-drug conjugate(ADC) that binds to ROR1 and B7-H3, uses for such ADCs, specifically the present invention relates to an antibody-drug conjugate comprising a bispecific antibody that specifically binds to ROR1 and B7-H3; and uses for such ADCs in treatment and/or prevention of diseases, more specifically cancer diseases.
Bibliography:Application Number: TW202211119008