Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing material thereof

A method for producing a compound represented by formula (1) or a salt thereof, the method comprising: a step B for producing a compound represented by formula (3) [in formula (3), Boc represents a tert-butoxycarbonyl group] or a salt thereof by using a compound represented by formula (2) [in formul...

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Main Authors OKUE, MASAYUKI, ISSHIKI, SATOSHI, SASAKI, TOSHIRO, FUSHIHARA, KENICHI, MOURI, SHINSUKE, TSUMURA, TAKESHI
Format Patent
LanguageChinese
English
Published 16.03.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A method for producing a compound represented by formula (1) or a salt thereof, the method comprising: a step B for producing a compound represented by formula (3) [in formula (3), Boc represents a tert-butoxycarbonyl group] or a salt thereof by using a compound represented by formula (2) [in formula (2), Ra represents a hydrogen atom or an optionally substituted arylmethyl group, Rb represents an optionally substituted alkyl group or a cyclic alkyl group, R3 represents a hydrogen atom, a halogen atom, or a thiazol-2-yl group, and Xa represents a hydrogen atom or a halogen atom] or a salt thereof; and a step C for producing the compound represented by formula (1) or a salt thereof by using the compound represented by formula (3) or a salt thereof.
Bibliography:Application Number: TW202211124459