RAS inhibitors

The invention features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.

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Bibliographic Details
Main Authors BUCKL, ANDREAS, CREGG, JAMES, PITZEN, JENNIFER, EDWARDS, ANNE V, BURNETT, G. LESLIE, KOLTUN, ELENA S, SEMKO, CHRISTOPHER, KNOX, JOHN E, GILL, ADRIAN L
Format Patent
LanguageChinese
English
Published 01.03.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.
Bibliography:Application Number: TW20220117013