RAS inhibitors

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexesthereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.

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Bibliographic Details
Main Authors CREGG, JAMES, BUCKL, ANDREAS, BURNETT, G. LESLIE, KOLTUN, ELENA S, LIU, YANG, KNOX, JOHN E, GILL, ADRIAN L, WILDES, DAVID E, LEE, BIANCA JENNIFER, SINGH, MALLIKA, AAY, NAING, RICE, MEGHAN A
Format Patent
LanguageChinese
English
Published 16.07.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexesthereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.
Bibliography:Application Number: TW202110134447