Platelet membrane coated nanoparticles and uses thereof

The present disclosure provides for platelet membrane coated nanoparticles that comprise, inter alia, an immunomodulating agent that is a toll-like receptor (TLR) agonist and/or an upregulator of the opioid growth factor receptor. Compositions, e.g., medicament delivery devices and pharmaceutical co...

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Bibliographic Details
Main Authors HAUSHALTER, KRISTOFER J, BAHMANI, BAHARAK, LUK, BRIAN T, ZHANG, JIE
Format Patent
LanguageChinese
English
Published 01.05.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides for platelet membrane coated nanoparticles that comprise, inter alia, an immunomodulating agent that is a toll-like receptor (TLR) agonist and/or an upregulator of the opioid growth factor receptor. Compositions, e.g., medicament delivery devices and pharmaceutical compositions, comprising the present nanoparticles are also provided. Uses of the present nanoparticles, including uses of the present nanoparticles for treating or preventing a neoplasm in a subject, are further provided.
Bibliography:Application Number: TW202110124257