Synthesis of substituted arylmethylureas, analogues, and crystalline forms thereof and methods of using same

The present disclosure includes synthetic methods for preparing certain substituted (hetero)arylmethyl urea compounds, compositions comprising the same, and crystalline forms thereof, which can be used to treat, ameliorate, and/or prevent hepatitis B virus (HBV) infections in a patient.

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Bibliographic Details
Main Authors SPINK, JAN MICHELLE, PALLERLA, MAHESH KUMAR, PAMULAPATI, GANAPATI REDDY
Format Patent
LanguageChinese
English
Published 16.04.2022
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure includes synthetic methods for preparing certain substituted (hetero)arylmethyl urea compounds, compositions comprising the same, and crystalline forms thereof, which can be used to treat, ameliorate, and/or prevent hepatitis B virus (HBV) infections in a patient.
Bibliography:Application Number: TW202110121665