Methods of treating multiple myeloma

Provided herein are methods of treating multiple myeloma (MM) using specific doses of an anti-B-cell migration antigen (BCMA) antibody, various dosing regimens, and optionally combination therapy with dexamethasone, an immunomodulatory agent (e.g., pomalinamide), an anti-CD38 antibody or antigen bin...

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Bibliographic Details
Main Authors JACQUEMONT, CELINE FABIENNE, TAFT, DAVID, LI, HONG, CAMPBELL, MARY, NEFF-LAFORD, HALEY, VAN EPPS, HEATHER
Format Patent
LanguageChinese
English
Published 16.01.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are methods of treating multiple myeloma (MM) using specific doses of an anti-B-cell migration antigen (BCMA) antibody, various dosing regimens, and optionally combination therapy with dexamethasone, an immunomodulatory agent (e.g., pomalinamide), an anti-CD38 antibody or antigen binding fragment thereof (e.g., daratumumab), and a gamma secretase inhibitor (GSI), and/or various combinations thereof.
Bibliography:Application Number: TW202110111220