Dual-targeted carbonic anhydrase IX complex and a contrast agent thereof

Disclosed herein are dual-targeted carbonic anhydrase IX complex, contrast agent comprising the same, and synthesizing method thereof. The dual-targeted carbonic anhydrase IX complex includes a carbonic anhydrase IX (CA9) binding peptide, sulfonamide derivatives, and a metal chelating agent connecte...

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Main Authors LUO, TSAI-YUEH, LIN, KUN-LIANG, PENG, CHENG-LIANG, LIAO, TSE-ZUNG, GUAN, SIAO-SYUN
Format Patent
LanguageChinese
English
Published 01.06.2021
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEASUREMENT OF NUCLEAR OR X-RADIATION
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SURGERY
TESTING
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Summary:Disclosed herein are dual-targeted carbonic anhydrase IX complex, contrast agent comprising the same, and synthesizing method thereof. The dual-targeted carbonic anhydrase IX complex includes a carbonic anhydrase IX (CA9) binding peptide, sulfonamide derivatives, and a metal chelating agent connected to each other. The dual-targeted carbonic anhydrase IX complex has potential for use as the molecular nuclear medicine.
Bibliography:Application Number: TW20198142431