Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof

The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method...

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Main Authors TSUNEMI, TOMOYUKI, NAKAYAMA, KIYOSHI, INAGAKI, HIROAKI, LAPIERRE, JEAN-MARC, EATHIRAJ, SUDHARSHAN, OTA, YUSUKE, SCHWARTZ, BRIAN, MOMOSE, TAKAYUKI, NAMDEV, NIVEDITA
Format Patent
LanguageChinese
English
Published 16.09.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
Bibliography:Application Number: TW20209114376