3,9-diazaspiro[5.5]undecane compounds

The present invention covers 3,9-diazaspiro[5.5]undecane compounds of general formula (I) and general formula (I-a): in which R1, R2, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and comb...

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Main Authors LIENAU, PHILIP, KOPITZ, CHARLOTTE CHRISTINE, PRECHTL, STEFAN, POTZE, LISETTE, KIRK, RALPH STEVEN, NOWAK-REPPEL, KATRIN, KUHNKE, LARA PATRICIA, WITTROCK, SVEN, GRAHAM, KEITH, LANGE, MARTIN, BADER, BENJAMIN, HEINRICH, TOBIAS, BUCHGRABER, PHILIPP, AIGUABELLA FONT, NURIA, BRAUER, NICO, STEUBER, HOLGER, HARVEY, REBECCA ANN
Format Patent
LanguageChinese
English
Published 01.07.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention covers 3,9-diazaspiro[5.5]undecane compounds of general formula (I) and general formula (I-a): in which R1, R2, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
Bibliography:Application Number: TW20198130633