Manufacturing process and intermediates for a pyrrolo [ 2,3-D] pyrimidine compound and use thereof

The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositi...

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Main Authors JONES, KRIS NICOLE, HILLS, ANDREW KEVERN, JONES, BRIAN PATRICK, LEWIS, CHAD ARTHUR, DEFOREST, JACOB COLE, ARORA, KAPILDEV KASHMIRILAL, RANE, ANIL MAHADEO
Format Patent
LanguageChinese
English
Published 16.05.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
Bibliography:Application Number: TW20198123441