Nitroxyl donors with improved therapeutic index

The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compo...

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Main Authors TOSCANO, JOHN P, FROST, LISA MARIE, KALISH, VINCENT JACOB, BROOKFIELD, FREDRICK ARTHUR, COURTNEY, STEPHEN MARTIN
Format Patent
LanguageChinese
English
Published 01.09.2019
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Summary:The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Bibliography:Application Number: TW20187143952