(E)-[alpha],[beta]-unsaturated amide compounds and the preparation method and use thereof

The present invention provides a novel class of (E)-[alpha],[beta]-unsaturated amide compounds represented by Formula I, and relates to a method for the preparation of such compounds and their use in the manufacture in a medicament. The compounds have an action of protecting nerve cells and an immun...

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Main Authors ZHAO, XU-YANG, LIU, WEI-WEI, FENG, REN-TIAN, BAI, HUA, ZHANG, XIN-LONG, GONG, YONG-XIANG, ZHU, YONG-LIN, LIU, LI-FEI, DING, FANG, ZHONG, JIN-QING, JI, KAI-GE, LI, YI, CHEN, WEN, GONG, YOU-JING
Format Patent
LanguageChinese
English
Published 01.04.2019
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a novel class of (E)-[alpha],[beta]-unsaturated amide compounds represented by Formula I, and relates to a method for the preparation of such compounds and their use in the manufacture in a medicament. The compounds have an action of protecting nerve cells and an immunomodulatory activity. The definitions of R1, R2 and R3 in formula I are given in the specification.
Bibliography:Application Number: TW20187130083