Hetroarylamine compounds for modulating the hedgehog pathway and preparing method and uses thereof

The present invention provides a compound of formula (I): wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention further provides a process for preparing...

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Bibliographic Details
Main Authors KUO, MANN-YAN, LEE, YING-SHUAN, YANG, JU-YING, LIU, CHIA-WEI, HSIEH, SELINE YOU-RONG, LU, YANN-YU
Format Patent
LanguageChinese
English
Published 01.09.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of formula (I): wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention further provides a process for preparing the compound.
Bibliography:Application Number: TW20176140517