Pyrazolyquinoline compounds and preparation methods and pharmaceutical compositions thereof

A Pyrazolyquinoline compound is disclosed, comprising: a quinolyl group, its C6 position is connected to a substituent R1, and R1 is a halogen atom; a pyrazolyl group; a first phenyl group; and a second phenyl group, wherein: the C2 position of the quinolyl group is connected to the C3 position or t...

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Bibliographic Details
Main Authors CHEN, YEH-LONG, TSENG, CHIN-KAI, TSENG, CHERNGYI, LEE, JINING, TSENG, CHIN-HUA
Format Patent
LanguageChinese
English
Published 01.03.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A Pyrazolyquinoline compound is disclosed, comprising: a quinolyl group, its C6 position is connected to a substituent R1, and R1 is a halogen atom; a pyrazolyl group; a first phenyl group; and a second phenyl group, wherein: the C2 position of the quinolyl group is connected to the C3 position or the C5 position of the pyrazolyl group; when in the first case, when the C2 position of the quinolyl group is connected to the C3 position of the pyrazolyl group, the C5 position of the pyrazolyl group is connected to the C4 position of the first phenyl group; and when in the second case, when the C2 position of the quinolyl group is connected to the C5 position of the pyrazolyl group, the C3 position of the pyrazolyl is connected to the C4 position of the first phenyl group; and N1 position of the pyrazolyl group is connected to the C4 position of the second phenyl group.
Bibliography:Application Number: TW20160127576