An apparatus for detecting cells being infected by human papillomavirus (HPV) and an detection method therefor

• Main Authors: CHENG, MING-HUI, KUO, YU-FEN, YU, TSUNGIH, PAN, PO-WEI, CHEN, YENUN
• Format: Patent
• Language: Chinese; English
• Published: 16.06.2017
• Subjects: BEER; BIOCHEMISTRY; CALCULATING; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPUTING; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; COUNTING; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention provides a method for detecting whether cells are infected by human papillomavirus (HPV), and the method includes: (a) capturing a contour of a cell of a cellular image, wherein the contour has a contour pixel thereon; (b) identifying a tangent line of the contour pixel on the contour to define a first side and a second side being opposite to the first side of the tangent line, wherein the first side indicates the intracellular region and the second side indicates the extracellular region; (c) calculating an average value for an optical parameter of the plurality pixels within the areas of the first side and the second side; and (d) determining whether the cell is infected by HPV based on whether the average value for the optical parameter within the area of the first side is less than that within the area of the second side.