Anti-alpha-V integrin antibody for the treatment of fibrosis and/or fibrotic disorders
The invention relates to the treatment of fibrosis and/or fibrotic diseases by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from fibrosis and/or fibrotic diseases, including but not limited to system...
Saved in:
Main Authors | , , , , , , , , |
---|---|
Format | Patent |
Language | Chinese English |
Published |
16.06.2017
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention relates to the treatment of fibrosis and/or fibrotic diseases by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from fibrosis and/or fibrotic diseases, including but not limited to systemic sclerosis (SSc). More specifically, the instant invention relates to the treatment of fibrotic diseases of the skin, lung, heart, liver and/or kidney by means of said antibody. Even more specifically, the instant invention relates to the administration of a recombinant, de-immunized monoclonal antibody targeting [alpha]v-integrins patients suffering from systemic sclerosis, including, but not limited to systemic sclerosis of the skin, lung, heart and/or kidney by means of the anti-alpha-v integrin antibody DI17E6 and structural mutants thereof. |
---|---|
Bibliography: | Application Number: TW20165138308 |