Method for producing parvovirus having high infectivity titer and high purity

Provided are: a parvovirus derived from an unconcentrated cell culture supernatant, said parvovirus having a high infectivity titer of 109 TCID50/mL or more and the ratio of the viral infectivity titer (TCID50/mL) of said parvovirus to an impurity protein concentration (ng/mL) exceeding 5000:1; and...

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Bibliographic Details
Main Authors YANAGIDA, KOICHIRO, SAWAMURA, YOSHIYUKI
Format Patent
LanguageChinese
English
Published 16.05.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided are: a parvovirus derived from an unconcentrated cell culture supernatant, said parvovirus having a high infectivity titer of 109 TCID50/mL or more and the ratio of the viral infectivity titer (TCID50/mL) of said parvovirus to an impurity protein concentration (ng/mL) exceeding 5000:1; and a method for producing such a parvovirus having a high infectivity titer and a high purity as described above.
Bibliography:Application Number: TW20165135428