NOTCH pathway signaling inhibitor compounds

The present invention provides compounds, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing said compounds, or a pharmaceutically acceptable salt thereof, useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing...

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Main Authors HIPSKIND, PHILIP ARTHUR, PATEL, BHARVIN KUMAR, WROBLESKI, AARON D, CLAY, JULIA MARIE, EDGE, ALBERT, GILL, JOHN C, ZHAO, GAI-YING, VAN ES, HELMUTH HENDRIKUS GERARDUS
Format Patent
LanguageChinese
English
Published 01.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing said compounds, or a pharmaceutically acceptable salt thereof, useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell loss, and inducing auditory hair cell generation.
Bibliography:Application Number: TW20165119456