Antibodies against OX40 and uses thereof

Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light ch...

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Main Authors LONBERG, NILS, MAURER, MARK, AANUR, PRAVEEN, LEMAR, HADIA, CAI, ZHEHONG, YANG, ZHENG, HAN, MICHELLE MINHUA, LEI, MING, JURE-KUNKEL, MARIA, THUDIUM, KENT B, MILBURN, CHRISTINA MARIA, WONG, SUSAN, BARNHART, BRYAN C, HATCHER, SANDRA V, WANG, XI-TAO, SRINIVASAN, MOHAN, GOKEMEIJER, JO, SELBY, MARK J, CHANG, HAN, FENG, YAN, GARCIA, MARIE-MICHELLE NAVARRO, QUIGLEY, MICHAEL, HUANG, CHRISTINE, HENNING, KARLA A, KEMPE, THOMAS D, KOZHICH ALEXANDER T, RAJPAL, ARVIND, KORMAN, ALAN J, GUIRNALDA, PATRICK, CHAKRABORTY, INDRANI, SHAO, XIANG, YAMNIUK AARON P, SCHWEIZER, LIANG, STEVENS, BRENDA L
Format Patent
LanguageChinese
English
Published 01.03.2017
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Bibliography:Application Number: TW20165116545