N-acylpyrrolidine ether tropomyosin-related kinase inhibitors

The present invention relates to compounds of Formula I described herein and their pharmaceutically acceptable salts, and their use in medicine, in particular as Trk antagonists.

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Bibliographic Details
Main Authors OMOTO, KIYOYUKI, GREASLEY, SAMANTHA ELIZABETH, MCALPINE, INDRAWAN JAMES, CUI, JINGRONG JEAN, BAGAL, SHARANJEET KAUR, SKERRATT, SARAH ELIZABETH, TRAN-DUBE, MICHELLE BICH, NINKOVIC, SACHA, NAGATA, ASAKO
Format Patent
LanguageChinese
English
Published 16.05.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of Formula I described herein and their pharmaceutically acceptable salts, and their use in medicine, in particular as Trk antagonists.
Bibliography:Application Number: TW20154125109