Method for identifying modulators of ABC transporter-mediated ATP release and use of said modulators for treating diseases

The present invention belongs to the field of pharmaceutical industry and relates to an in vitro method for identifying test compounds which are capable of modulating adenosine triphosphate (ATP) release from cells by inhibiting or stimulating an ATP-Binding Cassette Transporter (ABC Transporter)-me...

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Bibliographic Details
Main Author BREEDVELD, PAULINE
Format Patent
LanguageChinese
English
Published 16.01.2016
Subjects
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:The present invention belongs to the field of pharmaceutical industry and relates to an in vitro method for identifying test compounds which are capable of modulating adenosine triphosphate (ATP) release from cells by inhibiting or stimulating an ATP-Binding Cassette Transporter (ABC Transporter)-mediated transport of ATP. The invention further relates to compounds having the above capability for treating specific diseases.
Bibliography:Application Number: TW20143125602