TROPOMYOSIN-RELATED kinase inhibitors

The present invention relates to compounds of Formula I and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as TrkA antagonists.

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Bibliographic Details
Main Authors GREASLEY, SAMANTHA ELIZABETH, OMOTO, KIYOYUKI, MCALPINE, INDRAWAN JAMES, CUI, JINGRONG JEAN, BAGAL, SHARANJEET KAUR, STORER, ROBERT IAN, SKERRATT, SARAH ELIZABETH, NINKOVIC, SACHA, NAGATA, ASAKO, LUNNEY, ELIZABETH ANN, WARMUS, JOSEPH SCOTT
Format Patent
LanguageChinese
English
Published 16.12.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of Formula I and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as TrkA antagonists.
Bibliography:Application Number: TW20154114501