Thiophene-substituted tetracyclic compounds and methods of use thereof for the treatment of viral diseases

The present invention relates to novel Thiophene-Substituted Tetracyclic Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, A', R2, R3, R4 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Thiophene-Substitu...

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Main Authors CHEN, LEI, ZHONG, BIN, HU, BIN, YU, WEN-SHENG, KOZLOWSKI, JOSEPH A, HAO, JING-LAI, TONG, LING, WANG, WEI-JUN, WANG, DA-HAI, DWYER, MICHAEL, KIM, SEONG-HEON, SHEN, CHANG-MAO, SELYUTIN, OLEG, LEI, ZHI-XIN
Format Patent
LanguageChinese
English
Published 16.12.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel Thiophene-Substituted Tetracyclic Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, A', R2, R3, R4 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Thiophene-Substituted Tetracyclic Compound, and methods of using the Thiophene-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
Bibliography:Application Number: TW20143101676