Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HC...

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Main Authors SOLL, RICHARD, HE, SHU-WEN, MCCOMAS, CASEY C, DAI, XING, LIU, HONG, PALANI, ANANDAN, HABERMANN, JOERG, LAI, ZHONG, ZORN, NICHOLAS, WU, HAO, KOCH, UWE, LIVERTON, NIGEL J, PENG, XUAN-JIA, LI, PENG, NARJES, FRANK, DANG, QUNG
Format Patent
LanguageChinese
English
Published 01.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
Bibliography:Application Number: TW20121132849