Retinoid-liposomes for enhancing modulation of HSP47 expression

• Main Authors: PAYNE, JOSEPH E, LIU, YUN, AKOPIAN, VIOLETTA, KNOPOV, VICTOR, MINOMI, KENJIRO, AHMADIAN, MOHAMMAD, PERELMAN, LOREN A, TANAKA, YASUNOBU, FEINSTEIN, ELENA, AVKIN-NAHUM, SHARON, METT, IGOR, KALINSKI, HAGAR, WITTE, RICHARD P, YING, WENBIN, NIITSU, YOSHIRO
• Format: Patent
• Language: Chinese; English
• Published: 16.04.2013
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SUGARS

What is described are pharmaceutical compositions comprising a double stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPINH1_45a (SEQ ID...