Substituted imidazoquinoline derivatives

The present invention relates to substituted imidazo[4, 5-c]quinoline derivatives of formula (I), wherein R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of the present invention and their use in the treatment of di...

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Main Authors SHARMA, RAJIV, KUMAR, SANJAY, DEORE, VIJAYKUMAR BHAGWAN, AGARWAL, VEENA R, YEWALKAR, NILAMBARI NILKANTH, NAIK, NISHIGANDHA, DAGIA, NILESH
Format Patent
LanguageChinese
English
Published 16.02.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to substituted imidazo[4, 5-c]quinoline derivatives of formula (I), wherein R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of the present invention and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammation and angiogenesis related disorders.
Bibliography:Application Number: TW20110144566