Novel compounds

Therapeutic compounds are disclosed having the general formula (I) that are useful for the treatment of metabolic disorders, including type II diabetes. The compounds have activity as agonists of GPR119. Compounds having the stereochemistry of formula (Ia) may also demonstrate DPP-IV inhibitory acti...

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Main Authors PROCTER, MARTIN JAMES, JEEVARATNAM, REVATHY PERPETUA, SCHOFIELD, KAREN LESLEY, JOHNSTONE, CRAIG, STEWART, ALAN JOHN WILLIAM, SWAIN, SIMON ANDREW, BARBA, OSCAR, FRY, PETER TIMOTHY, DAVIS, SUSAN HELEN, GLEAVE, ROBERT JAMES, BERTRAM, LISA SARAH, CARSWELL, EMMA LOUISE, KEILY, JOHN
Format Patent
LanguageChinese
English
Published 16.12.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Therapeutic compounds are disclosed having the general formula (I) that are useful for the treatment of metabolic disorders, including type II diabetes. The compounds have activity as agonists of GPR119. Compounds having the stereochemistry of formula (Ia) may also demonstrate DPP-IV inhibitory activity.
Bibliography:Application Number: TW20110140728