6-(alkyl-or cycloalkyl-triazolopyridazine-sulfanyl)benzo-thiazole derivatives: preparation, and use as medicaments and as MET inhibitors

The invention relates to the novel products of formula (I): with R1 representing alkyl, cycloalkyl or cycloalkylalkyl; Rb representing a hydrogen atom or a fluorine atom W representing H; alkyl, cycloalkyl, heterocycloalkyl or COR with R representing cycloalkyl, heterocycloalkyl, alkyl; alkoxy, -O-h...

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Bibliographic Details
Main Authors UGOLINI, ANTONIO, NEMECEK, CONCEPTION, WENTZLER, SYLVIE, DAMOUR, DOMINIQUE, BACQUE, ERIC
Format Patent
LanguageChinese
English
Published 16.01.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to the novel products of formula (I): with R1 representing alkyl, cycloalkyl or cycloalkylalkyl; Rb representing a hydrogen atom or a fluorine atom W representing H; alkyl, cycloalkyl, heterocycloalkyl or COR with R representing cycloalkyl, heterocycloalkyl, alkyl; alkoxy, -O-heterocycloalkyl; or NHR2 with R2 representing H, cycloalkyl, heterocycloalkyl or alkyl; all optionally substituted; these products being in any isomer form, and the salts thereof, as medicaments, especially as MET inhibitors.
Bibliography:Application Number: TW20110110835