Pyrimidinyl-piperazines useful as D3/D2 receptor ligands

The present invention relates to new dopamine D3 and D2 ligands of formula (I): wherein R1, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to proce...

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Main Authors FARKAS, SANDOR, AGAINE CSONGOR, EVA, KISS, BELA, LASZY, JUDIT, BARTANE SZALAI, GIZELLA, DOMANY, GYORGY, SAGHY, KATALIN, GYERTYAN, ISTVAN, KOMLODI, ZSOLT, SCHMIDT, EVA
Format Patent
LanguageChinese
English
Published 16.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to new dopamine D3 and D2 ligands of formula (I): wherein R1, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes for preparing the same, to compositions containing the same and to their use in the treatment and/or prevention of conditions which requires modulation of dopamine receptors.
Bibliography:Application Number: TW200897125706