Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase

Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, an...

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Main Authors FOURIE, ANNE M, LIANG, JIMMY T, MANI, NEELAKANDHA S, GOMEZ, LAURENT, SANTILLAN, JR, TANIS, VIRGINIA M, GRICE, CHERYL A, CHROVIAN, CHRISTA C, KEARNEY, AARON M, BACANI, GENESIS M, LOCHNER, SUSANNE, SEPASSI, KIA, LEE-DUTRA, ALICE, DENG, XIAO-HU, LANDRY-BAYLE, ADRIENNE M, BROGGINI, DIEGO, WIENER, JOHN J. M, ZINSER, HARTMUT, CHEUNG, EUGENE Y, SAPPEY, KATHLEEN C, WICKBOLDT, ALVAH T
Format Patent
LanguageChinese
English
Published 16.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.
Bibliography:Application Number: TW200998111909