Abuse resistant melt extruded formulation having reduced alcohol interaction

The present invention relates to a melt-extruded dosage form having reduced drug-alcohol interaction, comprising: (a) an abuse relevant drug or a drug having potential for dose dumping in alcohol; and (b) a matrix having a polymer, copolymer or combinations thereof selected from a group of monomers...

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Bibliographic Details
Main Authors BURST, ALEXANDER, ROTH, WOLFGANG, ZIETSCH, MARTINA
Format Patent
LanguageChinese
English
Published 16.12.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a melt-extruded dosage form having reduced drug-alcohol interaction, comprising: (a) an abuse relevant drug or a drug having potential for dose dumping in alcohol; and (b) a matrix having a polymer, copolymer or combinations thereof selected from a group of monomers consisting of cellulose ether, cellulose ester, acrylic acid ester, methacrylic acid ester and natrium-alginate. wherein said matrix is melt extruded and wherein the dosage form has reduced drug-alcohol interaction.
Bibliography:Application Number: TW200998103158