Compounds

Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents wherein R3 presents CF3 or Cl-4alkyl; and R3a presents CF3 or C1-4alkyl; R4 presents hydrogen or methyl; Z is absent or presents (CH2)2, 0 or OCH2; A, J and...

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Bibliographic Details
Main Authors MIRGUET, OLIVIER, GELLIBERT, FRANCOISE JEANNE, DODIC, NERINA, BOUILLOT, ANNE MARIE JEANNE
Format Patent
LanguageChinese
English
Published 16.09.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents wherein R3 presents CF3 or Cl-4alkyl; and R3a presents CF3 or C1-4alkyl; R4 presents hydrogen or methyl; Z is absent or presents (CH2)2, 0 or OCH2; A, J and L each presents CH; or one of A, J and L presents N and the other two each presents CH; when A presents CH, R5 is selected from hydrogen, methyl, C1-4alkoxy, methoxy-C2-3alkoxy-, chloro or fluoro and R6 presents hydrogen; or when A presents N, R5 and R6 each presents hydrogen or one of R5 and R6 presents hydrogen and the other presents methyl; X represent wherein when both J and L presents CH, R8 presents hydrogen, chloro, fluoro, CF3, Cl-4alkyl or C1-4alkoxy in a meta or ortho position relative to the R9 substituent; or when one of J and L presents N, R8 presents hydrogen or halo; and R9 presents hydrogen, halo, CF3, OCF3, C1-4alkyl, C1-4alkoxy, CN, CDNR10R11, CO2R12 or N3, wherein R10 and R11 are independently s
Bibliography:Application Number: TW200897146531