Use of mequitazine in racemate or enantiomer form to prepare a drug to treat or prevent pathologies involving histamine H4 receptors

The present application relates to the use of 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, 10-[(3S)-1-azabicyclo[2. 2. 2]oct-3-ylmethyl]-10H-phenothiazine or 10-[(3R,3S)-l-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, or a pharmaceutically acceptable salt thereof, to prepare...

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Bibliographic Details
Main Authors CLERC, THIERRY, CUSSAC, DIDIER, PRZYBYLSKI, CHRISTOPHE, TISNE-VERSAILLES, JACKY
Format Patent
LanguageChinese
English
Published 01.08.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present application relates to the use of 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, 10-[(3S)-1-azabicyclo[2. 2. 2]oct-3-ylmethyl]-10H-phenothiazine or 10-[(3R,3S)-l-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, or a pharmaceutically acceptable salt thereof, to prepare a drug to prevent or treat pathologies involving histamine H4 receptor.
Bibliography:Application Number: TW200897145696