N-terminal modified interferon-alpha

A method of reducing formation of non-natural disulfide bonds in a mature IFN- by adding one or more amino acid residues to its N-terminus cystein. Also disclosed herein is the IFN- thus modified.

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Bibliographic Details
Main Authors WU, BRYAN, HSU, MING-PIN, SHEN, TSAI-KUEI, TENG, CHING-LEOU
Format Patent
LanguageChinese
English
Published 01.06.2009
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A method of reducing formation of non-natural disulfide bonds in a mature IFN- by adding one or more amino acid residues to its N-terminus cystein. Also disclosed herein is the IFN- thus modified.
Bibliography:Application Number: TW200897137779