Imidazopyrazines as protein kinase inhibitors

In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or Aurora kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations i...

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Main Authors KEREKES, ANGELA D, BELANGER, DAVID B, TAGAT, JAYARAM R, MANDAL, AMIT K, CURRAN, PATRICK J, KULKARNI, BHEEMASHANKAR A, ZHANG, YONGLIAN, ESPOSITE, SARA J, YU, TAO, XIAO, YUSHI, MENG, ZHAO-YANG, SIDDIQUI, ARSHAD M, DOLL, RONALD J
Format Patent
LanguageChinese
English
Published 16.03.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or Aurora kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or Aurora kinases using such compounds or pharmaceutical compositions.
Bibliography:Application Number: TW200897121942