Aryl sulfamide derivatives and methods of their use

The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of cond...

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Main Authors CRAWLEY, MATTHEW L, ZHANG, PUWEN, MAHANEY, PAIGE ERIN, VU, AN THIEN, COHN, STEPHEN TODD, KIM, CALLAIN YOUNGHEE, WOODWORTH, RICHARD PAGE, FENSOME, ANDREW, MANN, CHARLES WILLIAM, TRYBULSKI, EUGENE JOHN, GOLDBERG, JOEL ADAM, MARELLA, MICHAEL ANTHONY, SABATUCCI, JOSEPH P, TEREFENKO, EUGENE ANTHONY, JENKINS, DOUGLAS JOHN, O'NEILL, DAVID JOHN, MCCOMAS, CASEY CAMERON
Format Patent
LanguageChinese
English
Published 16.11.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
Bibliography:Application Number: TW200796147565