Prolyl hydroxylase inhibitors

The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.

Saved in:
Bibliographic Details
Main Authors JIN, JIAN, LIU, RONGGANG, WIGGALL, KENNETH, SHAW, ANTONY N, FITCH, DUKE M, DUFFY, KEVIN J
Format Patent
LanguageChinese
English
Published 01.04.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
Bibliography:Application Number: TW200796122207