Chemical compounds

Compounds of formula (I), and salts and pro-drugs thereof: wherein for example R1 is optionally substituted aryl or heteroaryl; Y is a linking group selected from, for example, a direct bond, and a (substituted) alkyl chain; R2 is an optionally substituted aryl, an optionally substituted cycloalkyl...

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Main Authors PLOWRIGHT, ALLEYN, DONALD, CRAIG SAMUEL, NOWAK, THORSTEN, MCCOULL, WILLIAM, BUTLIN, ROGER JOHN, BIRCH, ALAN MARTIN, BOWKER, SUZANNE SAXON
Format Patent
LanguageChinese
English
Published 01.10.2006
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Summary:Compounds of formula (I), and salts and pro-drugs thereof: wherein for example R1 is optionally substituted aryl or heteroaryl; Y is a linking group selected from, for example, a direct bond, and a (substituted) alkyl chain; R2 is an optionally substituted aryl, an optionally substituted cycloalkyl or an optionally substituted heterocyclic group; are described. Processes to make such compounds and their use as DGAT inhibitors, for example in the treatment of obesity, are also described.
Bibliography:Application Number: TW200594144264