Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds

Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, Csrc, Src, PRK2, FGFR3, Flt3, Lck, Mekl, PDK-1, GSK3 , EGFR, P70s6k, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Ret, and KDR kinases in animal...

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Main Authors STEINIG, ARNO G, KITCHIN, JOHN, SABA, IMAAD, SAMBROOK SMITH, COLIN PETER, FOREMAN, KENNETH, TAVARES, PAULA, DAWSON, GRAHAM, PANICKER, BIJOY, SADIQ, SHAZIA, WENG, QINGHUA, COX, MATTHEW, GATTRELL, WILLIAM, WILKES, ROBIN, BARBA, OSCAR, AHMED, SALEH, LI, AN-HU, PEGG, NEIL ANTHONY, SMYTH, DON, BLOXHAM, JASON, MA, LI FU, DONG, HANQING, STOLZ, KATHRYN
Format Patent
LanguageChinese
English
Published 16.05.2006
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Summary:Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, Csrc, Src, PRK2, FGFR3, Flt3, Lck, Mekl, PDK-1, GSK3 , EGFR, P70s6k, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Ret, and KDR kinases in animals, including humans, for the treatment and/or prevention of various diseases and conditions such as cancer.
Bibliography:Application Number: TW200594126065