Method of manufacturing t-20 and t-1249 peptides at commercial scale, and t-20 and t-1249 compositions related thereto

The present invention relates to an improved process for making commercial quantities of a T-20 or a T-1249 composition, or a fragment of a T-20 or a T-1249 composition. The improvement includes using a low void space resin and/or a surface functionalized resin optionally loaded with an amino acid o...

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Bibliographic Details
Main Authors ZIARNO, WITOLD ANDREW, MAIKNER, JOHN JOSEPH, BOHLING, JAMES CHARLES, ZABRODSKI, WILLIAM JOSEPH, KINZEY, MARLIN KENNETH
Format Patent
LanguageChinese
English
Published 16.02.2005
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to an improved process for making commercial quantities of a T-20 or a T-1249 composition, or a fragment of a T-20 or a T-1249 composition. The improvement includes using a low void space resin and/or a surface functionalized resin optionally loaded with an amino acid or amino acid derivative to create one or more T-20 or T-1249 fragments.
Bibliography:Application Number: TW200493103361