COMPOSES NOUVEAUX AGONISTES DE PPAR ET COMPOSITIONS LES CONTENANT

L'INVENTION CONCERNE DES COMPOSES DE FORMULE (I) : DANS LAQUELLE A, B, E, Z, R1, R2 , R3, R5 ET R6 REPRESENTENT DIVERS RADICAUX, ET W REPRESENTE UNE LIAISON OU DIVERS RADICAUX. ELLE CONCERNE EGALEMENT DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSITIONS...

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Bibliographic Details
Main Authors DAVID AUSTEN PERRY, CHERYL MYERS HAYWARD
Format Patent
LanguageFrench
Published 23.12.2005
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:L'INVENTION CONCERNE DES COMPOSES DE FORMULE (I) : DANS LAQUELLE A, B, E, Z, R1, R2 , R3, R5 ET R6 REPRESENTENT DIVERS RADICAUX, ET W REPRESENTE UNE LIAISON OU DIVERS RADICAUX. ELLE CONCERNE EGALEMENT DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSITIONS COMME ACTIVATEURS DE PPAR alpha , POUR LE TRAITEMENT DE DIVERSES MALADIES. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.
Bibliography:Application Number: TN2002SN00014